Wednesday, January 16, 2013

Link between pot smoking and IQ drop challenged

NEW YORK (AP) ? A new analysis is challenging a report that suggests regular marijuana smoking during the teen years can lead to a long-term drop in IQ. The analysis says the statistical analysis behind that conclusion is flawed.

The original study, reported last August, included more than 1,000 people who'd been born in the town of Dunedin, New Zealand. Their IQ was tested at ages 13 and 38, and they were asked about marijuana use periodically between those ages.

Researchers at Duke University and elsewhere found that participants who'd reported becoming dependent on pot by age 18 showed a drop in IQ score between ages 13 and 38. The findings suggest pot is harmful to the adolescent brain, the researchers said.

Not so fast, says an analysis published online Monday by the Proceedings of the National Academy of Sciences.

Ole Rogeberg of the Ragnar Frisch Center for Economic Research in Oslo, says the IQ trend might have nothing to do with pot. Rather, it may have emerged from differences among the study participants in socioeconomic status, or SES, which involves factors like income, education and occupation, he says.

He based his paper on a computer simulation. It traced what would happen to IQ scores over time if they were affected by differences in SES in ways suggested by other research, but not by smoking marijuana. He found patterns that looked just like what the Duke study found.

In an interview, Rogeberg said he's not claiming that his alternative explanation is definitely right, just that the methods and evidence in the original study aren't enough to rule it out. He suggested further analyses the researchers could do.

The Duke scientists, who learned of Rogeberg's analysis late last week, say they conducted new statistical tests to assess his proposed explanation. Their verdict: It's wrong. Rogeberg says they need to do still more work to truly rule it out.

Experts unconnected to the two papers said the Rogeberg paper doesn't overturn the original study. It "raises some interesting points and possibilities," but provides "speculation" rather than new data based on real people, said Dr. Duncan Clark, who studies alcohol and drug use in adolescents at the University of Pittsburgh.

Dr. Nora Volkow, director of the National Institute on Drug Abuse, said observational studies of people like the Duke work can't definitively demonstrate that marijuana cause irreversible effects on the brain. In an email, she said Rogeberg's paper "looks sound" but doesn't prove that his alternative explanation is correct.

___

Online:

Journal: http://pnas.org

___

Malcolm Ritter can be followed at http://www.twitter.com/malcolmritter

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/b2f0ca3a594644ee9e50a8ec4ce2d6de/Article_2013-01-14-US-SCI-Marijuana-Teen-IQ/id-1140827cb8734d33ac3ec747de882803

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Monday, January 14, 2013

Software development projects frequently fail -- why?

I have great respect for software developers. Because software is abstract, invisible and runs at extreme speeds, the people who are good at building it have to possess a particular talent at visualization and a willingness to use complex tools.

When software developers become project managers (PMs), they tend to rely on software tools to monitor, control and report on projects, just as non-technical PMs do. The problems that technologists have in management have to do with inexperience in people interaction, including conflict, collaboration and just plain old ability to listen well. If you?re a technologist in management, you can find more ideas on what to do about this in my book Get Out of the Way.

For the rest of PMs, there are lots of good tools,such as PERT and Gantt charts, but simply having good tools will not make your project succeed. Software development projects frequently fail to produce results that the customer or end-user wants. Why?

Here are three factors that contribute to the unruliness of software development projects:

1. Estimating the effort and time required to complete a task is difficult. Even when reasonable-looking requirements and specifications of a software package are provided, understanding the difficulty of development may require architecting multiple layers and investigating interactions with a complex environment. Since requirements are generally high-level items, and design has to be done at multiple levels, it is difficult to break down the work into ?pebble-sized? tasks and then to keep to a schedule with those tasks.

2. Designing an algorithm often takes experimentation. Engineering a software system requires trying out some things to see if they work, or testing multiple possible ways to implement something to find one with reasonable performance, for example. This aspect of software engineering is so prevalent that Fred Brooks in The Mythical Man-Month advised us to ?plan to throw one away.? He meant that at the completion of a complex software implementation (such as an operating system), the designers have learned so much that it is often best to start over and re-implement everything.

3. Assuring that a software implementation functions properly under all conditions may take as long as the design phase. In fact, you may never be able to prove proper functioning, because testing all combinations of conditions is impossible. At best, using test-automation tools and good intuition about where to look for errors, a software team can reduce the number of bugs at the time of a software release, but almost never to zero.

Scheduling a software project is made more difficult by the fact that additional tasks are always discovered during implementation. This is so prevalent that I learned long ago always to ask ?What remains to be done?? in addition to ?What have you completed?? You can count on the list of tasks to be done growing during the project.

One of the best countermeasures to all of these problems is to use Agile development methods. Iterative development with regular demonstrations of working software having incrementally greater functionality will help reduce uncertainty and increase the ability of a development team to adapt to a changing world. It also shortens the time between the initial charter of the project and the point where the customer says, ?but that?s not what I wanted.?

Even Agile will not save all projects. If you?d like to learn more about why not, join me for a free webinar, Why Agile Won?t Fix All Your Problems, or simply download the slides here
.
And good luck. The world needs software, so we all have to keep on trying to deliver it the best we can.

Source: http://svprojectmanagement.com/software-development-not-by-pert-alone

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Tribal Members To Take Part In Inauguration Parade

FARGO, ND -

More than 50 enrolled members of tribes in South Dakota and North Dakota will be walking in President Barack Obama's inauguration parade later this month.

Fifty-five?people representing the Three Affiliated Tribes of Fort Berthold, the Spirit Lake Nation, the Standing Rock Sioux Tribe, Sisseton Wahpeton Oyate and the Turtle Mountain Band of Chippewa will walk in the Jan. 21 parade.

Prairie Rose Seminole is helping organize the local tribes in the walk. She says she received a call when parade organizers realized it didn't have a delegation from North Dakota.

She says the participants range from seven-year-olds to veterans. Some plan to walk in traditional attire.

The group will participate in other inauguration events and also tour historical sites while in Washington.

? 2013 Associated Press. All rights reserved. Material may not be redistributed.

Source: http://www.keloland.com/newsdetail.cfm/tribal-members-to-take-part-in-inauguration-parade/?id=142385

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Saturday, January 12, 2013

DUP Threatens Legal Action Over Union Flag

Belfast City Council could face legal action over its decision to limit the flying of the union flag over City Hall following an official complaint by the DUP.

The DUP claims the action made multiple breaches of the council's own equality scheme.

It said the complaint was "the first step towards a formal complaint to the Equality Commission and ultimately possible legal action.

"The DUP is committed to pursuing all political avenues to overturning the disastrous decision by Sinn Fein, SDLP and the Alliance party and to repairing the harm to good relations and a shared future it has caused."


The move follows the first meeting of the unionist forum ? an initiative set up by DUP leader Peter Robinson and UUP leader Mike Nesbitt.

The forum was established as an attempt by the two unionist parties to encourage dialogue between unionists and loyalists angered by the situation at City Hall.

Today the forum meets members of the community in east Belfast.

Mike Nesbitt, Finance Minister Sammy Wilson and the Reverend Mervyn Gibson are expected to attend.

Brian Rea, chair of the policing board in NI, says he believes dialogue on the union flag issue will "bear fruit".

"I want to pay tribute to those who are endeavouring to take this by a different route," Mr Rea said.

"I believe the dialogue that has now commenced by the political leadership will bear fruit.

"Dialogue and not disorder is the way to resolve this."

(IT)

Source: http://www.4ni.co.uk/news.asp?id=156614

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Digg?s Users Doubled Since August, Now Has Over 10 Million User Emails On File

Diggv1Digg today took to its blog to share a bit of information about its user growth and monetization plans, now that it's been at?Betaworks?for nearly six months. The company said that Digg's user base has doubled since the Betaworks takeover in August, and it also confirmed that Digg's "Apps We Like" section is one of the site's first efforts to monetize the new property.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/spFhuEhDK-s/

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Simulating The Red Planet, On The Pale Blue Dot

Copyright ? 2013 National Public Radio. For personal, noncommercial use only. See Terms of Use. For other uses, prior permission required.

IRA FLATOW, HOST:

This is SCIENCE FRIDAY. I'm Ira Flatow. Ever wondered what it would be like to live on Mars? You wake up to the sun peeking over a red horizon. Outside, it's a balmy minus 94 degrees Fahrenheit. Time for breakfast, right? Mars has a little gravity, at least about third of the Earth, so at least your fried egg would probably stay in the pan. Better yet, at the end of the day you have 40 extra minutes to waste on Facebook or read a novel or tend your Martian garden. That's right, the Martian day, or sol, is 24 hours, 39 minutes and 35 seconds - just a bit longer than our days here on Earth. Well, before we actually send astronauts there, scientists are busy preparing for the trip here on Earth. They're creating Martian habitats all over the planet. They have one in the Arctic, in the Antarctic, in Russia, the Utah desert, even on the side of a Hawaiian volcano, to see how humans really fair with longer days, limited light and a different menu. Seems like a good idea to work out the kinks before that six month journey, right?

Well, here to talk about what's going on in these experiments are my guests: Kim Binsted is a co-investigator on the HI-SEAS Project, that's the Hawaii Space Exploration Analog and Simulation. She's also an associate professor at the University of Hawaii in Honolulu. And she joins us today from Hawaii Public Radio. Welcome to SCIENCE FRIDAY.

KIM BINSTED: Great to be here.

FLATOW: Welcome - Charles Czeisler is the Baldino professor of sleep medicine at Harvard Med School. He's also the chief of the division of sleep medicine at Brigham and Women's Hospital in Boston. He joins us from the BBC in Manchester, England. Welcome back to SCIENCE FRIDAY, Dr. Czeisler.

CHARLES CZEISLER: Thank you, Ira.

FLATOW: Dr. Binsted, you're working on a study to make a better, quote, "space menu." Tell us what's wrong with the old space menu. What are astronauts eating today and what should they be eating tomorrow on their way to Mars?

BINSTED: Well, that they have today on the space station tastes great but what they are essentially is individually pre-prepared meals. You'll get sort of a TV dinner chunk to heat up, maybe add some water to and eat. The problem with that is that once you have you pre-prepared, say, individual serving of lasagna, it will stay lasagna for the rest of time. It will never be anything else.

(LAUGHTER)

FLATOW: And if you're looking at a two-and-a-half year mission to Mars, it would be nice, probably, to have some variety. So what we're looking at is instead of sending pre-prepared meals, sending shelf-stable ingredients that the astronauts can combine into different dishes.

So you're giving them basically the kitchen pantry to take with them instead of the pre-made stuff?

BINSTED: That's right. It's a specialized pantry. It has to be shelf-stable. That means it needs to be able to last the length of the mission without go bad. But yeah, essentially that's what we're doing.

FLATOW: Yeah. And I'm looking at some of the ingredients here. You've got truffle oil, dried shiitake mushrooms, Korean chili paste. This is better than the stuff I'm eating now.

(LAUGHTER)

FLATOW: Well, if you think about it, the cost of food on Mars, the most of the cost is going to be getting it there. So truffle oil weighs the same as the canola, so we might well send the good stuff.

All right, Charles Czeisler, let's talk about the study out this week in the proceedings of the National Academy of Sciences about the Mars500 mission. You didn't take part in this particular study but tell me about this mission and what they found.

CZEISLER: What they found was that one of the most prominent issues that came up when they did the simulation was difficulty adapting their sleep-wake cycles to the conditions of the experiment. So they were there for about 17 months.

FLATOW: How many people were put where?

There were six months - excuse me, six people who were there for 17 months, and they simulated many of the aspects of travel to Mars, the confinement, being in an environment where you're with a particular crew the entire time. And they were about the same age as the crew members - current astronauts on the International Space Station are. And they had mission tasks to do and they had a simulated time when they landed on Mars. The only thing that they did not include in the simulation was the Martian day, that 40-minute extra time that needs to be factored in to adaptation to Mars. But even without that aspect, four out of the six crew members developed quite severe abnormalities in the timing of their sleep-wake schedule. One was unable to maintain the 24-hour day and began exhibiting what we call non-24-hour disorder, where every day he was going to bed and waking up about an hour later each day even though the rest of his crew and the rest of the activities were scheduled on a 24-hour day. A couple of the crew members had delayed sleep phase disorder where they were having trouble going to bed at night and trouble waking up in the morning.

CZEISLER: Another one split the timing of their sleep-wake schedule so that they were taking part of their sleep during day and part of it during the night. And yet another one was having trouble sleeping at night and trouble staying awake during the day.

FLATOW: Is lack of sleep - is that a real problem on a Mars mission if you're just basically on your way to Mars?

CZEISLER: Yes. Because what it does is it causes a deterioration of our ability to perform during the daytime. And in addition to that, there are adverse effects on the body as well as the brain. So in addition to increasing the risk for error and accident, which could be catastrophic on the way to Mars, it also causes difficulty even in metabolizing the meals that are being prepared.

So if we give a standard meal to someone whose circadian rhythms are disrupted and who's not getting enough sleep, and even if they've only been on that kind of a schedule for a few weeks, they already begin to go into a pre-metabolic state where their pancreas is no longer putting out enough insulin, even though their blood sugar levels are going higher.

FLATOW: Wow. 1-800-989-8255. Talking about a simulated trip to Mars. And Kim Binsted, you actually participated in one of those mock Mars mission a few years ago. And you did live on the Martian day, right?

BINSTED: Right. We were up at Mars on Devon Island for four months. And of those four months, we spent five weeks living on a Mars day. And the reason we could do this is we were out there in the Arctic summer, so there was very little natural light variation over 24 hours. It was bright all day. And we found that of our crew, seven, there were couple of us who were already suffering the kind of sleep disruption that has already been described. And those people got worst when we went onto Mars time. The rest of us - I mean I can speak personally. I loved it.

(LAUGHTER)

BINSTED: It was like having an extra bonus 40 minutes at the end of the day.

FLATOW: Is there any kind of, you know, I remember when I was in the Antarctic so many years ago, they talked about being there over the winter time when there were six months of darkness. And there was loneliness and actual - a predictable depression that people left alone for such a long time went through. Kim, did you see that? Charles? Do you think that they have to plan for something like that?

BINSTED: We didn't see it, but then again we were in quite a different circumstance. We had brightness all the time. We had sunlight all the time. So we didn't have the sort of depressing darkness that they would have in Antarctica or the artificial light only that they had at Mars500 in Russia.

FLATOW: Charles, wouldn't they have some artificial light somewhere?

CZEISLER: Well, they would, but the seasonal affective disorder occurs even here on Earth in the northern latitudes where they - especially during the winter when there's a reduced amount of sunlight every day. And that is something that would have to be of a concern in preparing for a mission to Mars.

And so one of the things that we learned in our laboratory when we did several mock missions simulating a trip to Mars where we included the Martian day was that specific counter-measures, in particular evening exposure to brighter lights, such as when they might have to be tending their Martian gardens and being in with the sunlight. Instead of like here on Earth, the farmers getting up with the chickens, we would advise that they spend the time - the brighter light exposure in the evening just before going to bed so that that would help facilitate their adaptation to the Martian day.

FLATOW: Mm-hmm. 1-800-989-8255. Let's go to the phones. Let's talk to Elaine in Sacramento. Hi, Elaine.

ELAINE (CALLER): Hi. How are you?

FLATOW: Fine. How are you? Go ahead, please.

(CALLER): I have a question about the ingredients in the pantry of available food stuff for the Mars-bound ship. I'm assuming this is kind of a high altitude. And I wondered, will there be people on board who know how to assemble these ingredients? In other words - the same question I would ask anybody here on Earth. You know how to cook? If you were given a basket of ingredients, would you know how to put them together to make a meal? Or will there be a chef on board?

FLATOW: Yeah. Would you choose people on a mission who knew how to cook, you know, and didn't bring water? Good question, Elaine. What do you think, Kim?

BINSTED: Well, we picked our crew according to their astronaut-like capabilities instead of their cooking abilities. So we've got quite a range in our crew. But just to make sure that everyone knew what they were doing, we gave them cooking lessons. Cornell had a workshop earlier this year. And it was great to see them learning how to work with these ingredients. They made all sorts of wonderful things. You'd be amazed what you can do with chef table's ingredients with a little bit of know-how.

FLATOW: Why is it that we always see so much hot sauce popular with astronauts all the time?

BINSTED: Yeah. That's commonly observed. And there's a couple possible reasons for that. One is that in microgravity the fluids shift in your body so you tend to get more congested. And as you know, the sense of smell is a really important part of your sense of taste. So if that shuts down, then maybe you want to start stimulating your taste buds in other ways. That's one possibility. Another is that space is a low sensory stimulation environment. So maybe people are looking psychologically for whatever stimulation they can get. And again turn to the hot sauce.

FLATOW: Can I give you...

BINSTED: Yet another possibility is that when you're in a closed, cramped space, it gets kind of smelly. And so maybe your sense of smell shuts down for those reasons. We're investigating all three of these ideas in our study.

FLATOW: Can I throw in a fourth possibility?

BINSTED: Mm-hmm.

FLATOW: The astronauts were all trained in Houston.

(LAUGHTER)

BINSTED: Very possibly that too.

FLATOW: Well, you know, Texas hot sauce. Maybe they're just used to doing that and they take it up with them to space; could be a very simple answer. 1-800-989-8255. Let's go to Mike in Harrisburg, Pennsylvania. Hi, Mike.

MIKE: Hey, great, fascinating subject, one that I actually follow pretty closely. I, for about two years, worked in a job where for three days a week I was basically locked inside with the same people. Keep in mind, I could go home for the other four days, but we are pretty much indoors for three consecutive days. And at the end of that time, we were basically at each other's throats.

I mean we just didn't like each other, even though we had all started out as fast friends, we're all grown professionals. And I just often think about this experience and how you will not - how you would prevent this from happening to astronauts that are going to be gone for two, two and half years on a Martian mission. And I also have the answer for hot sauce, if you're wondering.

FLATOW: Yeah. What's your hot sauce suggestion?

MIKE: It's very prevalent within the military. If you don't - you've never eaten it or used it in food, you learn very early on to use it. So these are all mostly, I'm guessing, naval aviators. They were exposed to it as young cadets at Annapolis or as young sailors or as young naval officers. So...

FLATOW: Yeah. Well, you know, some of the pay load specialists were not, but then again they were - I'm sticking with my Houston. And I'll go with your - I'll go with your military explanation. Thanks, Mike. 1-800-989-8255 is our number. We're talking about the missions to Mars on SCIENCE FRIDAY from NPR. And let me get to his question and answer. What about people at each other's throat? Charles?

CZEISLER: It is...

BINSTED: Well, what we...

CZEISLER: Go on.

BINSTED: I was just going to say that what we've learned with these crews is they tend to either do very well together and bond very closely, or things can go quite badly wrong. When things go wrong in these small groups, they can go quite badly wrong. So one possible solution is to just make sure that you've tested your crew as a crew in these kinds of environments to see how they do before you send them off. So maybe you send your Mars crew to Antarctica for a few months before you send them to Mars.

FLATOW: Do you agree, Charles?

CZEISLER: Yes, I agree. And there's also a developing set of technologies to recognize with safe observation when things are going wrong with crew members even if they're not talking about it. And Dr. David Dinges at the University of Pennsylvania is working on technology that would allow earlier detection of problems within a crew so that interventions can be deployed.

FLATOW: Kim Binsted, if we have an international crew of astronauts, not just from the United States, you're going to have to widen your menu a bit, are you not to...

BINSTED: Well, as you saw from our ingredients list, we're doing our best to keep it quite wide right now. But yes, you'll find that they way they combine these ingredients, of course, they'll have preferences on recipes and how they use them. Right now we're seeing that as a plus, that it'll provide more variety. But there could well be conflict if one crew member loves a particular dish and another one hates it. That could be a source of conflict rather than pleasure.

FLATOW: And you actually have a recipe contest going on now?

BINSTED: That's right. It's just - I think it's just opening today, so we're - we've posted our ingredient list on our website, hi-seas.org. And we invite people to go and send us their recipes, look at what we've got. And the finalists are going to be tried out by the crew when their in the habitat for four months. And yeah, prizes to the winners.

FLATOW: And when does the habitat begin? Give us the schedule on it.

BINSTED: It's going to be - they're right now in their training mission in Utah, and then they go into the habitat here in Hawaii at the beginning of April for four months.

FLATOW: And that's on the side of a mountain, a volcano?

BINSTED: That's right. It's on the slopes of Mauna Loa, and it's a wonderful area. It's extremely Mars-like. When you see pictures of it, it looks just like the images coming back from the rover on Mars right now. Very little plant life, all of this wonderful reddish regolith, very little sight of human activity, you know, a telescope off in the distance but not much else. It's not the sand and waving palm trees that you're thinking of necessarily.

FLATOW: But it's certainly not that episode on "The Twilight Zone" where the guy went a little nutty by himself. Remember that one? He thought he was alone in the town?

BINSTED: Let's hope it's not like that.

(LAUGHTER)

FLATOW: Any last words, Charles? Any last words of advice on people who are going to be going to space, to Mars?

CZEISLER: Well, I think maintaining - keeping their circadian rhythms in sync with a 24-hour day is going to be critical, and light is the most important synchronizer of our internal circadian rhythm. So coordinating the timing of light exposure is going to be crucial. And it's exciting that on the International Space Station, it's just being refitted with new solid-state lighting systems that are going to enable us to control the wavelength of the exposure and not just the intensity. And wavelength is critical because the shorter wavelength, the bluer end of the spectrum, is much more effective at resetting circadian rhythms.

FLATOW: There we go. Thank you all for taking time to be with us today. Have a good weekend.

BINSTED: Thank you.

CZEISLER: Thank you, Ira. Good afternoon.

FLATOW: You're welcome. Kim Binsted is co-investigator of the HI-SEAS project. That's the Hawaii Space Exploration Analog and Simulation, also associate professor at the University of Hawaii in Honolulu. You can get - go on our website and she's got that recipe contest up there. Charles Czeisler is the Baldino professor of sleep medicine at Harvard Med School, also chief of the division of sleep medicine at Brigham and Women's Hospital in Boston.

Copyright ? 2013 National Public Radio. All rights reserved. No quotes from the materials contained herein may be used in any media without attribution to National Public Radio. This transcript is provided for personal, noncommercial use only, pursuant to our Terms of Use. Any other use requires NPR's prior permission. Visit our permissions page for further information.

NPR transcripts are created on a rush deadline by a contractor for NPR, and accuracy and availability may vary. This text may not be in its final form and may be updated or revised in the future. Please be aware that the authoritative record of NPR's programming is the audio.

Source: http://www.npr.org/2013/01/11/169144855/simulating-the-red-planet-on-the-pale-blue-dot?ft=1&f=1007

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Thursday, January 10, 2013

Video: Mother of Tucson shooting victim: We must ?demand a plan? to end gun violence

Blinking gives your brain a break

Blink. Blink blink blink. Every minute, we blink our eyes 15 to 20 times. But we only need to blink two to four times a minute for adequate lubrication. So what's happening when we blink those other times? (Blink blink blink)

Source: http://video.msnbc.msn.com/hardball/50402502/

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